We track breakthroughs in aging and longevity from around the world — giving credit where it's due, without hype, bias, or commercial interest.
📡 Updated monthly. Free for everyone.
🆕 April 30, 2026 – First Full Archive
What's new this month
- 🧬 Rejuvenation: First human OSK trial (glaucoma/NAION) – added full citation
- 💊 Therapeutics: Probiotics + phytochemicals RCT – grip strength +4.4kg, lower inflammation
- 🧠 Cognitive Longevity: OVERTURE trial – 84% slower functional decline (full citation now live)
- 🤖 AI & Longevity: TNIK inhibitor – AI-discovered senomorphic (preclinical)
- 📊 Biomarkers & Diagnostics: Quinoa bioester – skin proteomic age reversal (~11–16 years)
- 🌍 Exposome & Lifestyle: Anti-inflammatory diet & skin cancer risk (2.19x higher risk)
- 🩺 Clinical Trials & Regulatory: SIRT6 gene therapy – 3-month safety trial in aged dogs
📬 All existing content from April 14 remains. These are additions — nothing removed, nothing repeated.
Browse by topic
🧬 Rejuvenation
Reversing or slowing biological age — epigenetic reprogramming, senolytics, gene therapy, partial reprogramming (global).
💊 Therapeutics
Drugs, supplements, clinical trials — metformin, rapamycin, fisetin, new senolytics, AI‑discovered compounds (global).
🧠 Cognitive Longevity
Brain health, dementia, mental aging — Alzheimer's research, light/sound therapy, nootropics, brain fog (global).
🌍 Exposome & Lifestyle
Environment, diet, exercise, social factors — pollution, sleep, stress, autonomic balance (global).
🤖 AI & Longevity
Artificial intelligence in aging research — AI drug discovery, predictive models, biomarker identification (global).
📊 Biomarkers & Diagnostics
Measuring aging — epigenetic clocks, piRNAs, blood tests, imaging (global).
🩺 Clinical Trials & Regulatory
Human studies, approvals, safety — Phase I/II/III trials, FDA approvals, TAME trial, OSK therapy (global).